Molybdenum storage protein prepared under in vivo-like conditions and incubated with ATP and molybdate at 303 K

Structure

x-ray diffraction · 2 distinct chains · 43% helix, 15% strand (DSSP).

Ligands and binding sites

• J7T · molybdate cluster · ligand · chains B, A
• J7N · 2,2,4-tris(oxidanyl)-1,3-dioxa-2$l^{4},4$l^{3}-dimolybdacyclobutane · ligand · chains B, A
• J8E · oxidanyl-[[2,2,4,4,4-pentakis($l^{1}-oxidanyl)-1-(oxidanylmolybdenio)-1$l^{3},3-dioxa-2$l^{5},4$l^{5}-dimolybdacyclobut-2-yl]oxy]molybdenum · ligand · chains B
• FUQ · Mo5 Cluster · ligand · chains B
• J7Q · tetrakis($l^{1}-oxidanyl)-[[2,2,2,4,4,4,4,6,6,6,8-undecakis($l^{1}-oxidanyl)-8-(oxidanylmolybdeniooxy)-6-[tris($l^{1}-oxidanyl)molybdeniooxy]-1,3,5,7-tetraoxa-2$l^{6},4$l^{6},6$l^{6},8$l^{4}-tetramolybdacyclooct-2-yl]oxy]molybdenum · ligand · chains A
• ATP · Adenosine-5'-triphosphate · ligand · chains B, A
• J8B · Molybdate cluster · ligand · chains A
• J85 · [[[bis(oxidanylmolybdenio)-$l^{3}-oxidanyl]-$l^{1}-oxidanyl-oxidanylidene-molybdenio]-(oxidanylmolybdenio)-$l^{3}-oxidanyl]-tetrakis($l^{1}-oxidanyl)molybdenum · ligand · chains A
• MG · Magnesium ion · metal · chains A
• MOO · Molybdate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Interfaces

1 interface between chains.

• B–A · 2280 Ų buried · 26 hydrogen bonds · protein-protein

Compared structures

• 6H8B · Molybdenum storage protein prepared under in vivo-like conditions and incubated with ATP… · the same entry in another collection · chain B against B, TM-score 1.00
• P84308 · AlphaFold monomer V2.0 prediction for molybdenum storage protein subunit alpha (P84308) · a predicted model of the same protein · chain A against A, TM-score 1.00
• P84253 · AlphaFold monomer V2.0 prediction for molybdenum storage protein subunit beta (P84253) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P84253
• Every structure of UniProt P84308
• Elsewhere: RCSB PDB 6H8B · PDBe 6H8B · UniProt P84253 · UniProt P84308