MolNFT v1 · #150750 · protein
Myxococcus xanthus mgla bound to GDP and pi with mixed inactive and active switch region conformations
6H35 · Mutual gliding-motility protein mgla: “Myxococcus xanthus mgla bound to GDP and pi with mixed inactive and active switch region conformations”. X-ray diffraction, 2 ligands (GDP, PO4), 8 pockets (best druggability 0.44). MolNFT v1…
- PDB
- 6H35
- Type
- protein
- Length
- 386 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mutual gliding-motility protein mgla
- UniProt
- Q1DB04
- Ligands
- GDP, PO4
- Pockets
- 8 · best druggability 0.44
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Mutual gliding-motility protein mgla | protein | 193 | 36% helix, 27% strand | Q1DB04 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains A, B
- PO4 · Phosphate ion · ion · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · 9 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 117 | 0.44 | 0.76 | 19 | empty |
| 2 | 97 | 0.41 | 0.77 | 15 | empty |
| 3 | 100 | 0.39 | 0.76 | 15 | empty |
| 4 | 77 | 0.39 | 0.77 | 17 | empty |
| 5 | 80 | 0.36 | 0.76 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 410 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 6H35 · Myxococcus xanthus MglA bound to GDP and Pi with mixed inactive and active switch region… · the same entry in another collection · chain A against A, TM-score 1.00
- Q1DB04 · AlphaFold monomer V2.0 prediction for mutual gliding-motility protein mgla (Q1DB04) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1DB04
- Elsewhere: RCSB PDB 6H35 · PDBe 6H35 · UniProt Q1DB04
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.