MolNFT v1 · #150742 · protein
Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA M6A1832 methyltransferase at 2.5A resolution
6H2V: “Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA M6A1832 methyltransferase at 2.5A resolution”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #150742 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6H2V
- Type
- protein
- Length
- 632 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9NRN9, Q9UI30
- Ligands
- SO4
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 211 | — | Q9NRN9 |
| B | — | protein | 111 | — | Q9UI30 |
| C | — | protein | 195 | — | Q9NRN9 |
| D | — | protein | 115 | — | Q9UI30 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 7 copies · chains A, B, C, D
- EDO · 1,2-ethanediol · additive · 2 copies · chains B, C, D
- PG0 · 2-(2-methoxyethoxy)ethanol · additive · 2 copies · chains A, C, D
- PEG · Di(hydroxyethyl)ether · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6H2V · Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA m6A1832 methyltransferase… · the same entry in another collection · chain B against B, TM-score 1.00
- Q9NRN9 · AlphaFold monomer V2.0 prediction for rRNA N6-adenosine- methyltransferase METTL5 (Q9NRN9) · a predicted model of the same protein · chain C against A, TM-score 0.96
- Q9UI30 · AlphaFold monomer V2.0 prediction for multifunctional methyltransferase subunit… · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NRN9
- Every structure of UniProt Q9UI30
- Elsewhere: RCSB PDB 6H2V · PDBe 6H2V · UniProt Q9NRN9 · UniProt Q9UI30
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