MolNFT v1 · #150671 · protein
Glycogen synthase kinase-3 beta (GSK3) complex with a covalent [1,2, 4]TRIAZOLO[1,5-A][1,3,5]TRIAZINE inhibitor
6H0U: “Glycogen synthase kinase-3 beta (GSK3) complex with a covalent [1,2, 4]TRIAZOLO[1,5-A][1,3,5]TRIAZINE…”. X-ray diffraction, 3 ligands (FKB, NA, CL). MolNFT v1 #150671 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6H0U
- Type
- protein
- Length
- 696 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P49841
- Ligands
- FKB, NA, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 348 | — | P49841 |
Ligands and binding sites
- FKB · (2~{R})-3-[7-azanyl-5-(cyclohexylamino)-[1,2, 4]triazolo[1,5-a][1,3,5]triazin-2-yl]-2-cyano-propanamide · ligand · 2 copies · chains A, B
- NA · Sodium ion · metal · chains B
- CL · Chloride ion · ion · 2 copies · chains B
- GOL · Glycerol · additive · 3 copies · chains A, B
- MLI · Malonate ion · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6H0U · Glycogen synthase kinase-3 beta (GSK3) complex with a covalent… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49841
- Elsewhere: RCSB PDB 6H0U · PDBe 6H0U · UniProt P49841
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