MolNFT v1 · #150018 · protein
USP15 catalytic domain structure
6GHA · Ubiquitin carboxyl-terminal hydrolase 15,UBIQUITIN…: “USP15 catalytic domain structure”. X-ray diffraction, 1 ligand (ZN), 4 pockets (best druggability 0.38). MolNFT v1 #150018 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6GHA
- Type
- protein
- Length
- 325 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin carboxyl-terminal hydrolase 15,UBIQUITIN carboxyl-terminal hydrolase 15
- EC
- 3.4.19.12
- UniProt
- Q9Y4E8
- Ligands
- ZN
- Pockets
- 4 · best druggability 0.38
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin carboxyl-terminal hydrolase 15,UBIQUITIN carboxyl-terminal hydrolase 15 (EC 3.4.19.12) | protein | 325 | 29% helix, 27% strand | Q9Y4E8 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.38 | 0.77 | 14 | empty |
| 2 | 86 | 0.33 | 0.74 | 22 | empty |
| 3 | 75 | 0.32 | 0.74 | 19 | empty |
| 4 | 63 | 0.32 | 0.75 | 10 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y4E8
- Elsewhere: RCSB PDB 6GHA · PDBe 6GHA · UniProt Q9Y4E8
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