MolNFT v1 · #149989 · protein
P53 cancer mutant Y220C in complex with small-molecule stabilizer PK9324
6GGD: “P53 cancer mutant Y220C in complex with small-molecule stabilizer PK9324”. X-ray diffraction, 2 ligands (EYB, ZN). MolNFT v1 #149989 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6GGD
- Type
- protein
- Length
- 394 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P04637
- Ligands
- EYB, ZN
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 196 | — | P04637 |
| B | — | protein | 198 | — | P04637 |
Ligands and binding sites
- EYB · [9-ethyl-7-(1,2-oxazol-4-yl)carbazol-3-yl]methyl-methyl-azanium · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · 2 copies · chains A, B
- GOL · Glycerol · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6GGD · p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9324 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04637
- Elsewhere: RCSB PDB 6GGD · PDBe 6GGD · UniProt P04637
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.