MolNFT v1 · #149815 · protein

Murine protein tyrosine phosphatase PTPN13 PDZ3 domain

6GBD: “Murine protein tyrosine phosphatase PTPN13 PDZ3 domain”. Solution nmr, 2 pockets (best druggability 0.72). MolNFT v1 #149815 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6GBD
Type: protein
Length: 119 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PDZ3
UniProt: Q64512
Pockets: 2 · best druggability 0.72

Structure

solution nmr · 1 distinct chain · 9% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PDZ3	protein	119	9% helix, 20% strand	Q64512

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	221	0.72	0.88	40	empty
2	120	0.46	0.78	26	empty

Compared structures

6GBD · Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain · the same entry in another collection · chain A against A, TM-score 1.00
Q64512 · AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type 13… · a predicted model of the same protein · chain A against A, TM-score 0.68

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q64512
Elsewhere: RCSB PDB 6GBD · PDBe 6GBD · UniProt Q64512

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