MolNFT v1 · #149674 · protein

Crystal structure of human carbonic anhydrase isozyme XII 2- (benzylamino)-4-chloro-N-(2-hydroxyethyl)-5-sulfamoyl-benzamide

6G7A: “Crystal structure of human carbonic anhydrase isozyme XII 2…”. X-ray diffraction, 2 ligands (EOQ, ZN). MolNFT v1 #149674 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6G7A
Type: protein
Length: 1,047 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O43570
Ligands: EOQ, ZN

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	—	protein	262	—	O43570
D	—	protein	261	—	O43570

Ligands and binding sites

EOQ · 4-chloranyl-~{N}-(2-hydroxyethyl)-2-[(phenylmethyl) amino]-5-sulfamoyl-benzamide · ligand · 4 copies · chains A, B, C, D
ZN · Zinc ion · metal · 4 copies · chains A, B, C, D
EDO · 1,2-ethanediol · additive · 12 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6G7A · Crystal structure of human carbonic anhydrase isozyme XII… · the same entry in another collection · chain D against D, TM-score 1.00
O43570 · AlphaFold monomer V2.0 prediction for carbonic anhydrase 12 (O43570) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43570
Elsewhere: RCSB PDB 6G7A · PDBe 6G7A · UniProt O43570

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