MolNFT v1 · #149298 · protein

Structure of an E333Q variant of the GH99 endo-alpha-mannanase from bacteroides xylanisolvens in complex with tetramannoside yeast mannan fragment

6FWG · Glycosyl hydrolase family 71: “Structure of an E333Q variant of the GH99 endo-alpha-mannanase from bacteroides xylanisolvens in complex with…”. X-ray diffraction, 2 ligands (MAN, MMA), 2 pockets (best druggability 0.49). MolNFT v1…

PDB: 6FWG
Type: protein
Length: 346 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycosyl hydrolase family 71
UniProt: D6D1V7
Ligands: MAN, MMA
Pockets: 2 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycosyl hydrolase family 71	protein	346	34% helix, 17% strand	D6D1V7

Ligands and binding sites

MAN · alpha-D-mannopyranose · sugar · 3 copies · chains A
MMA · methyl alpha-D-mannopyranoside · sugar · chains A
ACT · Acetate ion · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	161	0.49	0.77	26	MAN
2	50	0.33	0.78	16	empty

Compared structures

6FWG · Structure of an E333Q variant of the GH99 endo-alpha-mannanase from Bacteroides… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D6D1V7
Elsewhere: RCSB PDB 6FWG · PDBe 6FWG · UniProt D6D1V7

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