MolNFT v1 · #149015 · protein

Crystal structure of ephrin B4 (EPHB4) receptor protein kinase

6FNL · Ephrin type-B receptor 4: “Crystal structure of ephrin B4 (EPHB4) receptor protein kinase”. X-ray diffraction, 1 pocket (best druggability 0.61). MolNFT v1 #149015 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6FNL
Type: protein
Length: 262 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ephrin type-B receptor 4
EC: 2.7.10.1
UniProt: P54760
Pockets: 1 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ephrin type-B receptor 4 (EC 2.7.10.1)	protein	262	42% helix, 18% strand	P54760

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	268	0.61	0.80	33	empty

Compared structures

6FNL · Crystal Structure of Ephrin B4 (EphB4) Receptor Protein Kinase · the same entry in another collection · chain A against A, TM-score 1.00
P54760 · AlphaFold monomer V2.0 prediction for ephrin type-B receptor 4 (P54760) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P54760
Elsewhere: RCSB PDB 6FNL · PDBe 6FNL · UniProt P54760

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