MolNFT v1 · #149014 · protein
Crystal structure of ephrin B4 (EPHB4) receptor protein kinase with a PYRAZOLO[3,4-D]PYRIMIDINE fragment of nvp-BHG712
6FNK: “Crystal structure of ephrin B4 (EPHB4) receptor protein kinase with a PYRAZOLO[3,4-D]PYRIMIDINE fragment of…”. X-ray diffraction, 1 ligand (DXK). MolNFT v1 #149014 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FNK
- Type
- protein
- Length
- 274 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P54760
- Ligands
- DXK
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 274 | — | P54760 |
Ligands and binding sites
- DXK · 1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-amine · ligand · chains A
- EDO · 1,2-ethanediol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FNK · Crystal Structure of Ephrin B4 (EphB4) Receptor Protein Kinase with a… · the same entry in another collection · chain A against A, TM-score 1.00
- P54760 · AlphaFold monomer V2.0 prediction for ephrin type-B receptor 4 (P54760) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P54760
- Elsewhere: RCSB PDB 6FNK · PDBe 6FNK · UniProt P54760
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