MolNFT v1 · #149010 · protein
Crystal structure of ephrin A2 (EPHA2) receptor protein kinase with an isomer of nvp-BHG712
6FNG: “Crystal structure of ephrin A2 (EPHA2) receptor protein kinase with an isomer of nvp-BHG712”. X-ray diffraction, 1 ligand (DWT). MolNFT v1 #149010 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FNG
- Type
- protein
- Length
- 277 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P29317
- Ligands
- DWT
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 277 | — | P29317 |
Ligands and binding sites
- DWT · 4-methyl-3-[(2-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{N}-[3-(trifluoromethyl) phenyl]benzamide · ligand · chains A
- EDO · 1,2-ethanediol · additive · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P29317 · AlphaFold monomer V2.0 prediction for ephrin type-a receptor 2 (P29317) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29317
- Elsewhere: RCSB PDB 6FNG · PDBe 6FNG · UniProt P29317
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.