MolNFT v1 · #149003 · protein
Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-peg interactions in proteins
6FN9: “Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-peg interactions in proteins”. X-ray diffraction, 2 ligands (DW8, BEZ). MolNFT v1 #149003 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FN9
- Type
- protein
- Length
- 452 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P63104
- Ligands
- DW8, BEZ
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 228 | — | P63104 |
| B | — | protein | 224 | — | P63104 |
Ligands and binding sites
- DW8 · [2-[2-oxidanylidene-2-[[3-[2-[2-[2-[3-oxidanylidene-3-(propylamino) propoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]amino]etho xy]phenyl]phosphonic acid · ligand · 2 copies · chains A, B
- BEZ · Benzoic acid · ligand · 2 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FN9 · Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG… · the same entry in another collection · chain A against A, TM-score 1.00
- P63104 · AlphaFold monomer V2.0 prediction for 14-3-3 protein ZETA/DELTA (P63104) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63104
- Elsewhere: RCSB PDB 6FN9 · PDBe 6FN9 · UniProt P63104
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