MolNFT v1 · #14863 · protein
Crystal structure of galactose mutarotase from lactococcus lactis complexed with D-quinovose
1MMY · Aldose 1-epimerase: “Crystal structure of galactose mutarotase from lactococcus lactis complexed with D-quinovose”. X-ray diffraction, 2 ligands (G6D, NA), 7 pockets (best druggability 0.71). MolNFT v1 #14863 on GenesisL1: 3D…
- PDB
- 1MMY
- Type
- protein
- Length
- 685 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aldose 1-epimerase
- EC
- 5.1.3.3
- UniProt
- Q9ZB17
- Ligands
- G6D, NA
- Pockets
- 7 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 9% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aldose 1-epimerase (EC 5.1.3.3) | protein | 339 | 10% helix, 44% strand | Q9ZB17 |
| B | Aldose 1-epimerase (EC 5.1.3.3) | protein | 346 | 9% helix, 43% strand | Q9ZB17 |
Ligands and binding sites
- G6D · alpha-D-quinovopyranose · ligand · 2 copies · chains A, B
- NA · Sodium ion · metal · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 453 | 0.71 | 0.81 | 67 | empty |
| 2 | 168 | 0.61 | 0.83 | 29 | G6D |
| 3 | 175 | 0.60 | 0.82 | 31 | G6D |
| 4 | 62 | 0.34 | 0.77 | 17 | empty |
| 5 | 63 | 0.33 | 0.76 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 994 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 1MMY · Crystal structure of galactose mutarotase from Lactococcus lactis complexed with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ZB17
- Elsewhere: RCSB PDB 1MMY · PDBe 1MMY · UniProt Q9ZB17
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