MolNFT v1 · #148595 · protein + DNA
Crystal structure of the I-crei homing endonuclease D75N variant in complex with an altered version of its target DNA at 5NNN region in the presence of manganese
6FB9: “Crystal structure of the I-crei homing endonuclease D75N variant in complex with an altered version of its…”. X-ray diffraction, 1 ligand (MN). MolNFT v1 #148595 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FB9
- Type
- protein + DNA
- Length
- 355 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P05725
- Ligands
- MN
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | — | dna | 14 | — | — |
| C | — | dna | 14 | — | — |
| A | — | protein | 154 | — | P05725 |
| B | — | protein | 153 | — | P05725 |
| F | — | dna | 10 | — | — |
| D | — | dna | 10 | — | — |
Ligands and binding sites
- MN · Manganese (II) ion · metal · 5 copies · chains E, A, B, D, C, F
- PGO · S-1,2-propanediol · additive · 4 copies · chains A, B, F, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FB9 · Crystal Structure of the I-CreI Homing Endonuclease D75N variant in complex with an… · the same entry in another collection · chain D against D, TM-score 1.00
- P05725 · AlphaFold monomer V2.0 prediction for DNA endonuclease I-crei (P05725) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05725
- Elsewhere: RCSB PDB 6FB9 · PDBe 6FB9 · UniProt P05725
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