MolNFT v1 · #148555 · protein
Antibody derived (abd-5) small molecule binding to KRAS.
6FA2: “Antibody derived (abd-5) small molecule binding to KRAS.”. X-ray diffraction, 3 ligands (GNP, D2W, MG). MolNFT v1 #148555 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FA2
- Type
- protein
- Length
- 980 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P01116
- Ligands
- GNP, D2W, MG
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 167 | — | P01116 |
| B | — | protein | 168 | — | P01116 |
| C | — | protein | 165 | — | P01116 |
| D | — | protein | 158 | — | P01116 |
| E | — | protein | 164 | — | P01116 |
| F | — | protein | 158 | — | P01116 |
Ligands and binding sites
- GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · 6 copies · chains A, B, C, D, E, F
- D2W · 4-[2-(dimethylamino)ethoxy]-~{N}-[[(3~{R})-5-(6-methoxypyridin-2-yl)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]benzamide · ligand · 6 copies · chains A, B, C, D, E, F
- MG · Magnesium ion · metal · 6 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FA2 · Antibody derived (Abd-5) small molecule binding to KRAS. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01116
- Elsewhere: RCSB PDB 6FA2 · PDBe 6FA2 · UniProt P01116
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