MolNFT v1 · #148532 · protein
Model of the rift valley fever virus glycoprotein pentamer
6F9F: “Model of the rift valley fever virus glycoprotein pentamer”. Electron microscopy, 20 pockets (best druggability 0.80). MolNFT v1 #148532 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6F9F
- Type
- protein
- Length
- 3,660 residues
- Chains
- 10
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycoprotein
- UniProt
- A2T085, A2T072
- Pockets
- 20 · best druggability 0.80
Structure
electron microscopy · 2 distinct chains · 7% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, E, G, I | Glycoprotein | protein | 301 | 11% helix, 27% strand | A2T085 |
| B, D, F, H, J | Glycoprotein | protein | 431 | 5% helix, 50% strand | A2T072 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1134 | 0.80 | 0.81 | 120 | empty |
| 2 | 1041 | 0.80 | 0.81 | 90 | empty |
| 3 | 1057 | 0.80 | 0.81 | 108 | empty |
| 4 | 990 | 0.79 | 0.81 | 90 | empty |
| 5 | 784 | 0.79 | 0.82 | 73 | empty |
Interfaces
25 interfaces between chains.
- A–B · 1149 Ų buried · 15 hydrogen bonds · protein-protein
- G–H · 1112 Ų buried · 10 hydrogen bonds · protein-protein
- I–J · 1084 Ų buried · 9 hydrogen bonds · protein-protein
- C–D · 1040 Ų buried · 15 hydrogen bonds · protein-protein
- E–F · 1031 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 6F9F · Model of the Rift Valley fever virus glycoprotein pentamer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A2T085
- Every structure of UniProt A2T072
- Elsewhere: RCSB PDB 6F9F · PDBe 6F9F · UniProt A2T085 · UniProt A2T072
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