MolNFT v1 · #148462 · protein
Crystal structure of the human BUB1 kinase domain in complex with bay 1816032
6F7B: “Crystal structure of the human BUB1 kinase domain in complex with bay 1816032”. X-ray diffraction, 2 ligands (CVQ, MG). MolNFT v1 #148462 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6F7B
- Type
- protein
- Length
- 343 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O43683
- Ligands
- CVQ, MG
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 343 | — | O43683 |
Ligands and binding sites
- CVQ · 2-[3,5-bis(fluoranyl)-4-[[3-[5-methoxy-4-[(3-methoxypyridin-4-yl)amino]pyrimidin-2-yl]indazol-1-yl]methyl]phenoxy]ethanol · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6F7B · Crystal structure of the human Bub1 kinase domain in complex with BAY 1816032 · the same entry in another collection · chain A against A, TM-score 1.00
- O43683 · AlphaFold monomer V2.0 prediction for mitotic checkpoint SERINE/THREONINE-protein kinase… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43683
- Elsewhere: RCSB PDB 6F7B · PDBe 6F7B · UniProt O43683
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