MolNFT v1 · #148121 · protein
The transcriptional regulator prfa from listeria monocytogenes in complex with a ring-fused 2-pyridone (MK206) - unfolded hth motif
6EXK: “The transcriptional regulator prfa from listeria monocytogenes in complex with a ring-fused 2-pyridone…”. X-ray diffraction, 2 ligands (C2Q, NA). MolNFT v1 #148121 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6EXK
- Type
- protein
- Length
- 461 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P22262
- Ligands
- C2Q, NA
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 231 | — | P22262 |
| B | — | protein | 230 | — | P22262 |
Ligands and binding sites
- C2Q · [(3~{R})-3-carboxy-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azanium · ligand · 2 copies · chains A, B
- NA · Sodium ion · metal · 2 copies · chains A, B
- IPA · Isopropyl alcohol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6EXK · The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a… · the same entry in another collection · chain A against A, TM-score 1.00
- P22262 · AlphaFold monomer V2.0 prediction for listeriolysin regulatory protein (P22262) · a predicted model of the same protein · chain B against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22262
- Elsewhere: RCSB PDB 6EXK · PDBe 6EXK · UniProt P22262
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