MolNFT v1 · #148063 · protein + DNA
X-ray structure of the complex between human alpha thrombin and NU172, a DUPLEX/QUADRUPLEX 26-mer DNA aptamer, in the presence of potassium ions.
6EVV: “X-ray structure of the complex between human alpha thrombin and NU172, a DUPLEX/QUADRUPLEX 26-mer DNA…”. X-ray diffraction, 7 ligands (NAG, MAN, BMA). MolNFT v1 #148063 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6EVV
- Type
- protein + DNA
- Length
- 319 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00734
- Ligands
- NAG, MAN, BMA, GAL, SIA, NA, K
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | — | protein | 33 | — | P00734 |
| H | — | protein | 260 | — | P00734 |
| E | — | dna | 26 | — | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains H
- MAN · alpha-D-mannopyranose · sugar · 2 copies
- BMA · beta-D-mannopyranose · sugar
- GAL · beta-D-galactopyranose · sugar
- SIA · N-acetyl-alpha-neuraminic acid · sugar
- NA · Sodium ion · metal · chains H
- K · Potassium ion · metal · chains E
- GOL · Glycerol · additive · chains H, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6EVV · X-ray structure of the complex between human alpha thrombin and NU172, a… · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00734
- Elsewhere: RCSB PDB 6EVV · PDBe 6EVV · UniProt P00734
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