MolNFT v1 · #14796 · protein
Structural analysis of the domain interactions in der, a switch protein containing two GTPase domains
1MKY · Probable GTP-binding protein enga: “Structural analysis of the domain interactions in der, a switch protein containing two GTPase domains”. X-ray diffraction, 2 ligands (GDP, PO4), 4 pockets (best druggability 0.49). MolNFT v1…
- PDB
- 1MKY
- Type
- protein
- Length
- 407 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable GTP-binding protein enga
- UniProt
- Q9X1F8
- Ligands
- GDP, PO4
- Pockets
- 4 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable GTP-binding protein enga | protein | 407 | 38% helix, 23% strand | Q9X1F8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 136 | 0.49 | 0.79 | 21 | empty |
| 2 | 97 | 0.38 | 0.75 | 20 | empty |
| 3 | 86 | 0.35 | 0.75 | 13 | empty |
| 4 | 121 | 0.35 | 0.72 | 19 | empty |
Modifications
Observed in the structure: 7 modified (engineered).
Compared structures
- 1MKY · Structural Analysis of the Domain Interactions in Der, a Switch Protein Containing Two… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9X1F8 · AlphaFold monomer V2.0 prediction for GTPase der (Q9X1F8) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X1F8
- Elsewhere: RCSB PDB 1MKY · PDBe 1MKY · UniProt Q9X1F8
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