MolNFT v1 · #147897 · protein
A mamc-mic insertion in mbp scaffold at position K170
6EQZ · Maltose-binding periplasmic PROTEIN,TIGHTLY bound bacterial…: “A mamc-mic insertion in mbp scaffold at position K170”. X-ray diffraction, 1 ligand (GLC), 12 pockets (best druggability 0.86). MolNFT v1 #147897 on GenesisL1: 3D…
- PDB
- 6EQZ
- Type
- protein
- Length
- 1,510 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Maltose-binding periplasmic PROTEIN,TIGHTLY bound bacterial magnetic particle…
- UniProt
- P0AEY0, Q2W8S0
- Ligands
- GLC
- Pockets
- 12 · best druggability 0.86
Structure
x-ray diffraction · 3 distinct chains · 44% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Maltose-binding periplasmic PROTEIN,TIGHTLY bound bacterial magnetic particle PROTEIN,MALTOSE-binding periplasmic protein | protein | 377 | 44% helix, 21% strand | P0AEY0, Q2W8S0 |
| D | Maltose-binding periplasmic PROTEIN,TIGHTLY bound bacterial magnetic particle PROTEIN,MALTOSE-binding periplasmic protein | protein | 379 | 44% helix, 21% strand | P0AEY0, Q2W8S0 |
| G | Maltose-binding periplasmic PROTEIN,TIGHTLY bound bacterial magnetic particle PROTEIN,MALTOSE-binding periplasmic protein | protein | 377 | 45% helix, 21% strand | P0AEY0, Q2W8S0 |
Ligands and binding sites
- GLC · alpha-D-glucopyranose · sugar · 8 copies · chains A, B, D, G
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
12 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1024 | 0.86 | 0.87 | 128 | empty |
| 2 | 1053 | 0.84 | 0.85 | 117 | empty |
| 3 | 239 | 0.71 | 0.86 | 33 | GLC |
| 4 | 274 | 0.71 | 0.85 | 27 | GLC |
| 5 | 298 | 0.71 | 0.84 | 28 | GLC |
Interfaces
6 interfaces between chains.
- B–D · 1617 Ų buried · 18 hydrogen bonds · protein-protein
- A–G · 1536 Ų buried · 13 hydrogen bonds · protein-protein
- A–B · 964 Ų buried · 4 hydrogen bonds · protein-protein
- B–G · 78 Ų buried · 1 hydrogen bond · protein-protein
- A–D · 75 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AEY0
- Every structure of UniProt Q2W8S0
- Elsewhere: RCSB PDB 6EQZ · PDBe 6EQZ · UniProt P0AEY0 · UniProt Q2W8S0
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