MolNFT v1 · #147896 · protein

4TH kow domain of human HSPT5

6EQY · Transcription elongation factor SPT5: “4TH kow domain of human HSPT5”. Solution nmr, 1 pocket (best druggability 0.44). MolNFT v1 #147896 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6EQY
Type: protein
Length: 115 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcription elongation factor SPT5
UniProt: O00267
Pockets: 1 · best druggability 0.44

Structure

solution nmr · 1 distinct chain · 0% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcription elongation factor SPT5	protein	115	0% helix, 45% strand	O00267

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	147	0.44	0.75	27	empty

Compared structures

6EQY · 4th KOW domain of human hSpt5 · the same entry in another collection · chain A against A, TM-score 1.00
O00267 · AlphaFold monomer V2.0 prediction for transcription elongation factor SPT5 (O00267) · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O00267
Elsewhere: RCSB PDB 6EQY · PDBe 6EQY · UniProt O00267

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