MolNFT v1 · #147684 · protein
Crystal structure of the human BRPF1 bromodomain complexed with BZ054 in space group C2
6EKQ: “Crystal structure of the human BRPF1 bromodomain complexed with BZ054 in space group C2”. X-ray diffraction, 2 ligands (B0H, NO3). MolNFT v1 #147684 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6EKQ
- Type
- protein
- Length
- 228 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P55201
- Ligands
- B0H, NO3
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 116 | — | P55201 |
| B | — | protein | 112 | — | P55201 |
Ligands and binding sites
- B0H · ~{N}-[4-[[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]methyl]-1,3-thiazol-2-yl]-2,4-dimethyl-1,3-oxazole-5-carboxamide · ligand · 2 copies · chains A, B
- NO3 · Nitrate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6EKQ · Crystal structure of the human BRPF1 bromodomain complexed with BZ054 in space group C2 · the same entry in another collection · chain A against A, TM-score 1.00
- P55201 · AlphaFold monomer V2.0 prediction for peregrin (P55201) · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P55201
- Elsewhere: RCSB PDB 6EKQ · PDBe 6EKQ · UniProt P55201
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