MolNFT v1 · #147660 · protein
The metal ion-dependent adhesion site (midas) of the ALPHAMBETA2 integrin mac-1 I-domain promiscuously and competitively binds multiple ligands in the regulation of leukocyte function
6EJX: “The metal ion-dependent adhesion site (midas) of the ALPHAMBETA2 integrin mac-1 I-domain promiscuously and…”. X-ray diffraction. MolNFT v1 #147660 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6EJX
- Type
- protein
- Length
- 532 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O35930
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D, A | — | protein | 266 | — | O35930 |
Ligands and binding sites
- POL · N-propanol · additive · 4 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · 3 copies · chains D, A
- IMD · Imidazole · additive · 2 copies · chains D, A
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · 2 copies · chains D, A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6EJX · The metal ion-dependent adhesion site (MIDAS) of the alphaMbeta2 integrin Mac-1 I-domain… · the same entry in another collection · chain D against D, TM-score 1.00
- O35930 · AlphaFold monomer V2.0 prediction for platelet glycoprotein ib alpha chain (O35930) · a predicted model of the same protein · chain D against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O35930
- Elsewhere: RCSB PDB 6EJX · PDBe 6EJX · UniProt O35930
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