MolNFT v1 · #14762 · protein
Catalytic domain of intron endonuclease I-tevi, E75A mutant
1MK0 · Intron-associated endonuclease 1: “Catalytic domain of intron endonuclease I-tevi, E75A mutant”. X-ray diffraction, 1 pocket (best druggability 0.48). MolNFT v1 #14762 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1MK0
- Type
- protein
- Length
- 97 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Intron-associated endonuclease 1
- EC
- 3.1.-.-
- UniProt
- P13299
- Pockets
- 1 · best druggability 0.48
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Intron-associated endonuclease 1 (EC 3.1.-.-) | protein | 97 | 39% helix, 22% strand | P13299 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 121 | 0.48 | 0.79 | 26 | CIT |
Modifications
Observed in the structure: 1 covalent (additive adduct).
Compared structures
- 1MK0 · catalytic domain of intron endonuclease I-TevI, E75A mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13299
- Elsewhere: RCSB PDB 1MK0 · PDBe 1MK0 · UniProt P13299
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