MolNFT v1 · #14761 · protein

Structure of inorganic pyrophosphatase mutant D97N

1MJZ: “Structure of inorganic pyrophosphatase mutant D97N”. X-ray diffraction, 2 pockets (best druggability 0.54). MolNFT v1 #14761 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1MJZ
Type: protein
Length: 175 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Inorganic pyrophosphatase
EC: 3.6.1.1
UniProt: P0A7A9
Pockets: 2 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 21% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Inorganic pyrophosphatase (EC 3.6.1.1)	protein	175	21% helix, 33% strand	P0A7A9

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	174	0.54	0.79	28	empty
2	56	0.32	0.77	17	empty

Compared structures

1MJZ · Structure of inorganic pyrophosphatase mutant D97N · the same entry in another collection · chain A against A, TM-score 1.00
P0A7A9 · AlphaFold monomer V2.0 prediction for inorganic pyrophosphatase (P0A7A9) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A7A9
Elsewhere: RCSB PDB 1MJZ · PDBe 1MJZ · UniProt P0A7A9

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