MolNFT v1 · #147456 · protein
Halk in complex with compound 1 (S)-N-(1-(2,4-DIFLUOROPHENYL)ETHYL)-3- (3-methyl-1H-pyrazol-5-YL)IMIDAZO[1,2-B]PYRIDAZIN-6-amine
6EDL: “Halk in complex with compound 1 (S)-N-(1-(2,4-DIFLUOROPHENYL)ETHYL)-3…”. X-ray diffraction, 1 ligand (J4M). MolNFT v1 #147456 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6EDL
- Type
- protein
- Length
- 282 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9UM73
- Ligands
- J4M
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 282 | — | Q9UM73 |
Ligands and binding sites
- J4M · N-[(1S)-1-(2,4-difluorophenyl)ethyl]-3-(5-methyl-1H-pyrazol-3-yl)imidazo[1,2-b]pyridazin-6-amine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6EDL · hALK in complex with compound 1 (S)-N-(1-(2,4-difluorophenyl)ethyl)-3-(3-methyl-1H-pyrazol… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UM73 · AlphaFold monomer V2.0 prediction for ALK tyrosine kinase receptor (Q9UM73) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UM73
- Elsewhere: RCSB PDB 6EDL · PDBe 6EDL · UniProt Q9UM73
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