MolNFT v1 · #147358 · protein
Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant K394R-S398L stabilized in the prefusion state
6EAH: “Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor escape variant…”. X-ray diffraction, 3 ligands (NAG, FUC, SO4). MolNFT v1 #147358 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6EAH
- Type
- protein
- Length
- 1,325 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- W8RJF9
- Ligands
- NAG, FUC, SO4
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 446 | — | W8RJF9 |
| B | — | protein | 440 | — | W8RJF9 |
| C | — | protein | 439 | — | W8RJF9 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains C
- FUC · alpha-L-fucopyranose · sugar · chains C
- SO4 · Sulfate ion · ion · 20 copies · chains A, C, B
- NHE · 2-[N-cyclohexylamino]ethane sulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6EAH · Crystal structure of human respiratory syncytial virus fusion glycoprotein inhibitor… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt W8RJF9
- Elsewhere: RCSB PDB 6EAH · PDBe 6EAH · UniProt W8RJF9
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