MolNFT v1 · #147294 · protein
Legionella longbeachae lesh (LLO2327) bound to the human interleukin-2 receptor beta PTYR387 peptide
6E8K: “Legionella longbeachae lesh (LLO2327) bound to the human interleukin-2 receptor beta PTYR387 peptide”. X-ray diffraction, 1 pocket (best druggability 0.34). MolNFT v1 #147294 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6E8K
- Type
- protein
- Length
- 160 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lesh (LLO2327); Interleukin-2 receptor beta PTYR387 peptide
- UniProt
- D3HJY4, P14784
- Pockets
- 1 · best druggability 0.34
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lesh (LLO2327) | protein | 157 | 38% helix, 18% strand | D3HJY4 |
| B | Interleukin-2 receptor beta PTYR387 peptide | protein | 3 | 0% helix, 0% strand | P14784 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 74 | 0.34 | 0.76 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 376 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 6E8K · Legionella Longbeachae LeSH (Llo2327) bound to the human interleukin-2 receptor beta… · the same entry in another collection · chain A against A, TM-score 1.00
- P14784 · AlphaFold monomer V2.0 prediction for interleukin-2 receptor subunit beta (P14784) · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D3HJY4
- Every structure of UniProt P14784
- Elsewhere: RCSB PDB 6E8K · PDBe 6E8K · UniProt D3HJY4 · UniProt P14784
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