UniProt P14784
Interleukin-2 receptor subunit beta (P14784)
Interleukin-2 receptor subunit beta (UniProt P14784): 14 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14784
- Protein
- Interleukin-2 receptor subunit beta
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 8 · 0 records with a druggable one
Structures
15 records of P14784 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B5I | cytokine receptor complex | x-ray diffraction | B | — | — |
| 2B5I | Cytokine receptor complex | x-ray diffraction | B | — | — |
| 2ERJ | Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 | x-ray diffraction | B, F | — | — |
| 2ERJ | Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 | x-ray diffraction | B, F | — | — |
| 3QAZ | IL-2 mutant D10 ternary complex | x-ray diffraction | B, E, H, K, N, Q, T, W, Z, c, f, i | — | — |
| 3QAZ | Il-2 mutant D10 ternary complex | x-ray diffraction | B, E, H, K, N, Q, T, W, Z, c, f, i | — | — |
| 4GS7 | Structure of the Interleukin-15 quaternary complex | x-ray diffraction | B | — | — |
| 4GS7 | Structure of the interleukin-15 quaternary complex | x-ray diffraction | B | — | — |
| 5M5E | Crystal structure of a interleukin-2 variant in complex with interleukin-2 receptor | x-ray diffraction | B | NAG, FUC, MAN, SO4, CYS | 5 (best 0.47) |
| 5M5E | Crystal structure of a interleukin-2 variant in complex with interleukin-2 receptor | x-ray diffraction | B | NAG, FUC, MAN, SO4 | — |
| 6E8K | Legionella Longbeachae LeSH (Llo2327) bound to the human interleukin-2 receptor beta pTyr387 peptide | x-ray diffraction | B | — | — |
| 6E8K | Legionella longbeachae lesh (LLO2327) bound to the human interleukin-2 receptor beta PTYR387 peptide | x-ray diffraction | B | — | — |
| 7S2S | nanobody bound to Interleukin-2Rbeta | x-ray diffraction | B, D | NAG, FUC, BMA, SO4 | 3 (best 0.40) |
| 7S2S | Nanobody bound to interleukin-2RBETA | x-ray diffraction | B, D | NAG, FUC, BMA, SO4 | — |
| P14784 | AlphaFold monomer V2.0 prediction for interleukin-2 receptor subunit beta (P14784) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6E8K chain B against the predicted model P14784: TM-score 1.00, RMSD 0.01 Å
- 6E8K chain B against the predicted model P14784: TM-score 1.00, RMSD 0.01 Å
- 4GS7 chain B against the predicted model P14784: TM-score 0.99, RMSD 0.39 Å
- 4GS7 chain B against the predicted model P14784: TM-score 0.99, RMSD 0.39 Å
- 2B5I chain B against the predicted model P14784: TM-score 0.99, RMSD 0.40 Å
- 2B5I chain B against the predicted model P14784: TM-score 0.99, RMSD 0.40 Å
- 3QAZ chain B against the predicted model P14784: TM-score 0.99, RMSD 0.50 Å
- 3QAZ chain B against the predicted model P14784: TM-score 0.99, RMSD 0.50 Å
- 3QAZ chain E against the predicted model P14784: TM-score 0.99, RMSD 0.54 Å
- 3QAZ chain E against the predicted model P14784: TM-score 0.99, RMSD 0.54 Å
Elsewhere
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