MolNFT v1 · #147178 · protein + DNA
Structure of tert in complex with a novel telomerase inhibitor
6E53: “Structure of tert in complex with a novel telomerase inhibitor”. X-ray diffraction, 2 ligands (HUV, MG). MolNFT v1 #147178 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6E53
- Type
- protein + DNA
- Length
- 619 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q0QHL8
- Ligands
- HUV, MG
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 596 | — | Q0QHL8 |
| E | — | dna | 23 | — | — |
Ligands and binding sites
- HUV · methyl 1-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-D-erythro-pentofuranosyl}-1H-indole-5-carboxylate · ligand · chains A, E
- MG · Magnesium ion · metal · 2 copies · chains A, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6E53 · Structure of TERT in complex with a novel telomerase inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0QHL8
- Elsewhere: RCSB PDB 6E53 · PDBe 6E53 · UniProt Q0QHL8
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