MolNFT v1 · #147066 · protein
Crystal structure of a maug-like protein associated with microbial copper homeostasis
6E1C · Di-heme enzyme: “Crystal structure of a maug-like protein associated with microbial copper homeostasis”. X-ray diffraction, 2 ligands (HEC, CA), 10 pockets (best druggability 0.86). MolNFT v1 #147066 on GenesisL1: 3D structure…
- PDB
- 6E1C
- Type
- protein
- Length
- 673 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Di-heme enzyme
- UniProt
- A0A2D2CY72
- Ligands
- HEC, CA
- Pockets
- 10 · best druggability 0.86
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Di-heme enzyme | protein | 350 | 33% helix, 5% strand | A0A2D2CY72 |
| B | Di-heme enzyme | protein | 323 | 30% helix, 5% strand | A0A2D2CY72 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 354 | 0.86 | 0.95 | 50 | HEC, CA |
| 2 | 382 | 0.85 | 0.93 | 51 | HEC |
| 3 | 417 | 0.79 | 0.88 | 51 | HEC |
| 4 | 388 | 0.79 | 0.88 | 48 | HEC |
| 5 | 244 | 0.51 | 0.75 | 40 | empty |
Interfaces
1 interface between chains.
- A–B · 382 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 cofactor (heme c attachment).
Compared structures
- 6E1C · Crystal structure of a MauG-like protein associated with microbial copper homeostasis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A2D2CY72
- Elsewhere: RCSB PDB 6E1C · PDBe 6E1C · UniProt A0A2D2CY72
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