MolNFT v1 · #147043 · protein

Structure of elizabethkingia meningoseptica cdne cyclic dinucleotide synthase with GTP and apcpp

6E0N · CGAS/DNCV-like nucleotidyltransferase in E. COLI homolog: “Structure of elizabethkingia meningoseptica cdne cyclic dinucleotide synthase with GTP and apcpp”. X-ray diffraction, 3 ligands (GTP, APC, MG), 1 pocket (best druggability…

PDB: 6E0N
Type: protein
Length: 271 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CGAS/DNCV-like nucleotidyltransferase in E. COLI homolog
Ligands: GTP, APC, MG
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CGAS/DNCV-like nucleotidyltransferase in E. COLI homolog	protein	271	47% helix, 18% strand	—

Ligands and binding sites

GTP · Guanosine-5'-triphosphate · ligand · 2 copies · chains A
APC · Diphosphomethylphosphonic acid adenosyl ester · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	749	0.71	0.77	49	APC, GTP, MG

Compared structures

6E0N · Structure of Elizabethkingia meningoseptica CdnE cyclic dinucleotide synthase with GTP… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6E0N · PDBe 6E0N

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