MolNFT v1 · #147035 · protein

Crystal structure of glucokinase in complex with compound 6

6E0E: “Crystal structure of glucokinase in complex with compound 6”. X-ray diffraction, 2 ligands (HKM, GLC). MolNFT v1 #147035 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6E0E
Type: protein
Length: 448 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P35557
Ligands: HKM, GLC

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	448	—	P35557

Ligands and binding sites

HKM · 2-({2-[(4-methyl-1,3-thiazol-2-yl)amino]pyridin-3-yl}oxy)benzonitrile · ligand · chains A
GLC · alpha-D-glucopyranose · sugar · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6E0E · Crystal structure of Glucokinase in complex with compound 6 · the same entry in another collection · chain A against A, TM-score 1.00
P35557 · AlphaFold monomer V2.0 prediction for hexokinase-4 (P35557) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35557
Elsewhere: RCSB PDB 6E0E · PDBe 6E0E · UniProt P35557

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