MolNFT v1 · #146923 · protein
Crystal structure of the viral otu domain protease from dera ghazi khan virus
6DX2 · RNA-dependent RNA polymerase: “Crystal structure of the viral otu domain protease from dera ghazi khan virus”. X-ray diffraction, 5 pockets (best druggability 0.75). MolNFT v1 #146923 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6DX2
- Type
- protein
- Length
- 312 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA-dependent RNA polymerase
- UniProt
- A0A191KW82
- Pockets
- 5 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | RNA-dependent RNA polymerase | protein | 156 | 40% helix, 24% strand | A0A191KW82 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 208 | 0.75 | 0.90 | 29 | empty |
| 2 | 121 | 0.49 | 0.80 | 32 | empty |
| 3 | 70 | 0.43 | 0.80 | 14 | empty |
| 4 | 65 | 0.41 | 0.80 | 13 | empty |
| 5 | 68 | 0.33 | 0.75 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 853 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6DX2 · Crystal structure of the viral OTU domain protease from Dera Ghazi Khan virus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A191KW82
- Elsewhere: RCSB PDB 6DX2 · PDBe 6DX2 · UniProt A0A191KW82
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