MolNFT v1 · #146575 · protein
Oligomeric structure of the HIV GP41 mper-tmd in phospholipid bilayers
6DLN · Transmembrane protein GP41: “Oligomeric structure of the HIV GP41 mper-tmd in phospholipid bilayers”. Solid-state nmr, 2 pockets (best druggability 0.51). MolNFT v1 #146575 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6DLN
- Type
- protein
- Length
- 117 residues
- Chains
- 3
- Method
- solid-state nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transmembrane protein GP41
- UniProt
- P04578
- Pockets
- 2 · best druggability 0.51
Structure
solid-state nmr · 1 distinct chain · 82% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Transmembrane protein GP41 | protein | 39 | 82% helix, 0% strand | P04578 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 168 | 0.51 | 0.77 | 19 | empty |
| 2 | 85 | 0.46 | 0.81 | 11 | empty |
Interfaces
3 interfaces between chains.
- A–B · 361 Ų buried · 1 hydrogen bond · protein-protein
- A–C · 347 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 276 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6DLN · Oligomeric Structure of the HIV gp41 MPER-TMD in Phospholipid Bilayers · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04578
- Elsewhere: RCSB PDB 6DLN · PDBe 6DLN · UniProt P04578
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