MolNFT v1 · #146270 · protein
Lpoa N-terminal domain from haemophilus influenzae; monoclinic form at 1.35 a resolution
6DCJ · Penicillin-binding protein activator lpoa: “Lpoa N-terminal domain from haemophilus influenzae; monoclinic form at 1.35 a resolution”. X-ray diffraction, 1 ligand (CL), 5 pockets (best druggability 0.64). MolNFT v1 #146270 on…
- PDB
- 6DCJ
- Type
- protein
- Length
- 442 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Penicillin-binding protein activator lpoa
- UniProt
- P45299
- Ligands
- CL
- Pockets
- 5 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Penicillin-binding protein activator lpoa | protein | 221 | 74% helix, 0% strand | P45299 |
Ligands and binding sites
- CL · Chloride ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 147 | 0.64 | 0.86 | 24 | CL |
| 2 | 140 | 0.62 | 0.86 | 26 | CL |
| 3 | 282 | 0.58 | 0.78 | 41 | empty |
| 4 | 50 | 0.29 | 0.75 | 11 | empty |
| 5 | 54 | 0.26 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 484 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 6DCJ · LpoA N-terminal domain from Haemophilus influenzae; monoclinic form at 1.35 A resolution · the same entry in another collection · chain A against A, TM-score 1.00
- P45299 · AlphaFold monomer V2.0 prediction for penicillin-binding protein activator lpoa (P45299) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P45299
- Elsewhere: RCSB PDB 6DCJ · PDBe 6DCJ · UniProt P45299
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.