MolNFT v1 · #14605 · protein
Human glycinamide ribonucleotide transformylase at pH 4.2
1MEO · Phosophoribosylglycinamide formyltransferase: “Human glycinamide ribonucleotide transformylase at pH 4.2”. X-ray diffraction, 2 ligands (PO4, SO4), 1 pocket (best druggability 0.51). MolNFT v1 #14605 on GenesisL1: 3D structure…
- PDB
- 1MEO
- Type
- protein
- Length
- 202 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosophoribosylglycinamide formyltransferase
- EC
- 2.1.2.2
- UniProt
- P22102
- Ligands
- PO4, SO4
- Pockets
- 1 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosophoribosylglycinamide formyltransferase (EC 2.1.2.2) | protein | 202 | 36% helix, 24% strand | P22102 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 255 | 0.51 | 0.75 | 31 | empty |
Compared structures
- 1MEO · human glycinamide ribonucleotide Transformylase at pH 4.2 · the same entry in another collection · chain A against A, TM-score 1.00
- P22102 · AlphaFold monomer V2.0 prediction for trifunctional purine biosynthetic protein… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22102
- Elsewhere: RCSB PDB 1MEO · PDBe 1MEO · UniProt P22102
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