MolNFT v1 · #145933 · protein
JAK2 pseudokinase V617F in complex with AT9283
6D2I: “JAK2 pseudokinase V617F in complex with AT9283”. X-ray diffraction, 1 ligand (35R). MolNFT v1 #145933 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6D2I
- Type
- protein
- Length
- 545 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q506Q0
- Ligands
- 35R
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 273 | — | Q506Q0 |
| B | — | protein | 272 | — | Q506Q0 |
Ligands and binding sites
- 35R · 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6D2I · JAK2 Pseudokinase V617F in complex with AT9283 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q506Q0
- Elsewhere: RCSB PDB 6D2I · PDBe 6D2I · UniProt Q506Q0
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