GL1X · GenesisL1 explorer

UniProt Q506Q0

Tyrosine-protein kinase (Q506Q0)

Tyrosine-protein kinase (UniProt Q506Q0), EC 2.7.10.2: 4 experimental structures on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q506Q0
Protein
Tyrosine-protein kinase
EC
2.7.10.2
Experimental structures
4
Predicted models
0
Ligands
2
Pockets
21 · 3 records with a druggable one

Structures

4 records of Q506Q0 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6D2IJAK2 Pseudokinase V617F in complex with AT9283x-ray diffractionA, B35R8 (best 0.69)
6D2IJAK2 pseudokinase V617F in complex with AT9283x-ray diffractionA, B35R8 (best 0.69)
6G3CCrystal Structure of JAK2-V617F pseudokinase domain in complex with Compound 2x-ray diffractionA, BEKT5 (best 0.74)
6G3CCrystal structure of JAK2-V617F pseudokinase domain in complex with compound 2x-ray diffractionA, BEKT—

Ligands

  • 35R · 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea · in 2 records
  • EKT · 2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7,7-trimethyl-8-(3-methylbutyl)pteridin-6-one · in 2 records

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.