MolNFT v1 · #145920 · protein
Crystal structure of tyrosine-protein kinase receptor
6D22: “Crystal structure of tyrosine-protein kinase receptor”. X-ray diffraction, 4 pockets (best druggability 0.67). MolNFT v1 #145920 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6D22
- Type
- protein
- Length
- 299 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosine-protein kinase receptor
- EC
- 2.7.10.1
- UniProt
- J3KP20
- Pockets
- 4 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein kinase receptor (EC 2.7.10.1) | protein | 299 | 38% helix, 16% strand | J3KP20 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 491 | 0.67 | 0.78 | 44 | empty |
| 2 | 157 | 0.58 | 0.82 | 25 | empty |
| 3 | 80 | 0.31 | 0.73 | 23 | empty |
| 4 | 51 | 0.26 | 0.73 | 14 | empty |
Compared structures
- 6D22 · Crystal structure of Tyrosine-protein kinase receptor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt J3KP20
- Elsewhere: RCSB PDB 6D22 · PDBe 6D22 · UniProt J3KP20
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