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UniProt J3KP20

Tyrosine-protein kinase receptor (J3KP20)

Tyrosine-protein kinase receptor (UniProt J3KP20), EC 2.7.10.1: 9 experimental structures on GenesisL1, 3 ligands bound, 10 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
J3KP20
Protein
Tyrosine-protein kinase receptor
EC
2.7.10.1
Experimental structures
9
Predicted models
0
Ligands
3
Pockets
10 · 3 records with a druggable one

Structures

9 records of J3KP20 in the MolNFT archive: 9 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6D22Crystal structure of Tyrosine-protein kinase receptorx-ray diffractionA—4 (best 0.67)
6D22Crystal structure of tyrosine-protein kinase receptorx-ray diffractionA——
6DKWCrystal structure of trk-a in complex with the pan-trk kinase inhibitor, compound 3.x-ray diffractionA, BGXA—
7VKMCrystal structure of TrkA (G595R) kinase domainx-ray diffractionA——
7VKMCrystal structure of trka (G595R) kinase domainx-ray diffractionA——
7VKNCrystal structure of TrkA (G595R) kinase with repotrectinibx-ray diffractionA7GI, SO43 (best 0.70)
7VKNCrystal structure of trka (G595R) kinase with repotrectinibx-ray diffractionA7GI, SO4—
7VKOCrystal structure of TrkA kinase with repotrectinibx-ray diffractionA7GI, SO43 (best 0.65)
7VKOCrystal structure of trka kinase with repotrectinibx-ray diffractionA7GI, SO4—

Ligands

  • 7GI · Repotrectinib · in 4 records
  • SO4 · Sulfate ion · in 4 records
  • GXA · 5-(1-methyl-1H-imidazol-4-yl)-2-[(1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl) oxy]benzamide · in 1 record

Elsewhere

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