MolNFT v1 · #145856 · protein

Crystal structure of kynurenine aminotransferase-II in apo-form, at 1.47 a resolution

6D0A · KYNURENINE/ALPHA-aminoadipate aminotransferase…: “Crystal structure of kynurenine aminotransferase-II in apo-form, at 1.47 a resolution”. X-ray diffraction, 5 pockets (best druggability 0.45). MolNFT v1 #145856 on GenesisL1: 3D…

PDB: 6D0A
Type: protein
Length: 431 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: KYNURENINE/ALPHA-aminoadipate aminotransferase, mitochondrial
EC: 2.6.1.39, 2.6.1.7
UniProt: Q8N5Z0
Pockets: 5 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	KYNURENINE/ALPHA-aminoadipate aminotransferase, mitochondrial (EC 2.6.1.39, 2.6.1.7)	protein	431	41% helix, 15% strand	Q8N5Z0

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	189	0.45	0.74	31	empty
2	93	0.45	0.80	21	empty
3	78	0.42	0.80	24	empty
4	66	0.37	0.77	15	empty
5	65	0.35	0.77	16	empty

Compared structures

6D0A · Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution · the same entry in another collection · chain A against A, TM-score 1.00
Q8N5Z0 · AlphaFold monomer V2.0 prediction for KYNURENINE/ALPHA-aminoadipate aminotransferase… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N5Z0
Elsewhere: RCSB PDB 6D0A · PDBe 6D0A · UniProt Q8N5Z0

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