Structure of alpha-GSA[26,6P] bound by CD1D and in complex with the VA14VB8.2 TCR

Structure

x-ray diffraction · 4 distinct chains.

Ligands and binding sites

• EM4 · N-[(2S,3S,4R)-3,4-dihydroxy-8-oxo-8-[(6-phenylhexyl) amino]-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octan-2-yl]hexacosanamide · ligand · chains C, A
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A
• FUC · alpha-L-fucopyranose · sugar · chains A
• NA · Sodium ion · metal · 4 copies · chains C, D, A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6CXE · Structure of alpha-GSA[26,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR · the same entry in another collection · chain C against C, TM-score 1.00
• P01887 · AlphaFold monomer V2.0 prediction for beta-2-microglobulin (P01887) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A0A0R4J090
• Every structure of UniProt P01887
• Elsewhere: RCSB PDB 6CXE · PDBe 6CXE · UniProt A0A0R4J090 · UniProt P01887