MolNFT v1 · #145648 · protein + DNA
Structure of human DNA polymerase beta complexed with 8-clg in the template base paired with incoming non-hydrolyzable CTP and manganese
6CU9: “Structure of human DNA polymerase beta complexed with 8-clg in the template base paired with incoming…”. X-ray diffraction, 3 ligands (0KX, MN, NA). MolNFT v1 #145648 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6CU9
- Type
- protein + DNA
- Length
- 357 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P06746
- Ligands
- 0KX, MN, NA
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 326 | — | P06746 |
| T | — | dna | 16 | — | — |
| P | — | dna | 10 | — | — |
| D | — | dna | 5 | — | — |
Ligands and binding sites
- 0KX · 2'-deoxy-5'-O-[(R)-hydroxy{[(r)-hydroxy(phosphonooxy) phosphoryl]amino}phosphoryl]cytidine · ligand · chains A, T, P
- MN · Manganese (II) ion · metal · 2 copies · chains A, P
- NA · Sodium ion · metal · 2 copies · chains A, P, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6CU9 · Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired… · the same entry in another collection · chain A against A, TM-score 1.00
- P06746 · AlphaFold monomer V2.0 prediction for DNA polymerase beta (P06746) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06746
- Elsewhere: RCSB PDB 6CU9 · PDBe 6CU9 · UniProt P06746
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