MolNFT v1 · #145506 · protein

TBK1 in complex with sulfone analog of amlexanox

6CQ5: “TBK1 in complex with sulfone analog of amlexanox”. X-ray diffraction, 1 ligand (F8S). MolNFT v1 #145506 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6CQ5
Type: protein
Length: 602 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9UHD2
Ligands: F8S

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	602	—	Q9UHD2

Ligands and binding sites

F8S · 2-amino-7-(1,1-dioxo-1lambda~6~-thian-4-yl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6CQ5 · TBK1 in Complex with Sulfone Analog of Amlexanox · the same entry in another collection · chain A against A, TM-score 1.00
Q9UHD2 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase TBK1 (Q9UHD2) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UHD2
Elsewhere: RCSB PDB 6CQ5 · PDBe 6CQ5 · UniProt Q9UHD2

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