MolNFT v1 · #145468 · protein
Sdca in complex with the E2, UBCH5C
6CP0: “Sdca in complex with the E2, UBCH5C”. X-ray diffraction, 8 pockets (best druggability 0.58). MolNFT v1 #145468 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6CP0
- Type
- protein
- Length
- 660 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sdca; Ubiquitin-conjugating enzyme E2 D3
- EC
- 2.3.2.23, 2.3.2.24
- UniProt
- Q6RCR3, P61077
- Pockets
- 8 · best druggability 0.58
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sdca | protein | 511 | 48% helix, 9% strand | Q6RCR3 |
| B | Ubiquitin-conjugating enzyme E2 D3 (EC 2.3.2.23, 2.3.2.24) | protein | 149 | 38% helix, 17% strand | P61077 |
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 138 | 0.58 | 0.83 | 23 | empty |
| 2 | 122 | 0.43 | 0.77 | 17 | empty |
| 3 | 53 | 0.41 | 0.82 | 16 | empty |
| 4 | 50 | 0.38 | 0.81 | 14 | empty |
| 5 | 73 | 0.36 | 0.76 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 634 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6RCR3
- Every structure of UniProt P61077
- Elsewhere: RCSB PDB 6CP0 · PDBe 6CP0 · UniProt Q6RCR3 · UniProt P61077
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.