MolNFT v1 · #145257 · protein
PYRUVATE:FERREDOXIN oxidoreductase from moorella thermoacetica with lactyl-tpp bound
6CIO: “PYRUVATE:FERREDOXIN oxidoreductase from moorella thermoacetica with lactyl-tpp bound”. X-ray diffraction, 5 ligands (SF4, TDL, TPP). MolNFT v1 #145257 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6CIO
- Type
- protein
- Length
- 6,960 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q2RMD6
- Ligands
- SF4, TDL, TPP, MG, SO4
Structure
x-ray diffraction · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 1164 | — | Q2RMD6 |
| C | — | protein | 1161 | — | Q2RMD6 |
| D | — | protein | 1159 | — | Q2RMD6 |
| E | — | protein | 1157 | — | Q2RMD6 |
| F | — | protein | 1155 | — | Q2RMD6 |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · 18 copies · chains A, B, C, D, E, F
- TDL · 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-(1-carboxy-1-hydroxyethyl)-5-(2-{[hydroxy(phosphonooxy) phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium · ligand · 4 copies · chains A, C, D, F
- TPP · Thiamine diphosphate · ligand · 2 copies · chains B, E
- MG · Magnesium ion · metal · 6 copies · chains A, B, C, D, E, F
- SO4 · Sulfate ion · ion · 7 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6CIO · Pyruvate:ferredoxin oxidoreductase from Moorella thermoacetica with lactyl-TPP bound · the same entry in another collection · chain F against F, TM-score 1.00
- Q2RMD6 · AlphaFold monomer V2.0 prediction for PYRUVATE:FERREDOXIN oxidoreductase (Q2RMD6) · a predicted model of the same protein · chain C against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2RMD6
- Elsewhere: RCSB PDB 6CIO · PDBe 6CIO · UniProt Q2RMD6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.