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MolNFT v1 · #144940 · protein

Crystal structure of fcrn bound to ucb-84

6C98: “Crystal structure of fcrn bound to ucb-84”. X-ray diffraction, 1 ligand (ER7). MolNFT v1 #144940 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6C98
Type
protein
Length
724 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P55899, P61769
Ligands
ER7

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, C—protein263—P55899
B, D—protein99—P61769

Ligands and binding sites

  • ER7 · 1-[7-(3-fluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethan-1-one · ligand · 2 copies · chains A, B, C, D
  • GOL · Glycerol · additive · 2 copies · chains B, D
  • PEG · Di(hydroxyethyl)ether · additive · chains B, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6C98 · Crystal structure of FcRn bound to UCB-84 · the same entry in another collection · chain D against D, TM-score 1.00
  • P55899 · AlphaFold monomer V2.0 prediction for IgG receptor fcrn large subunit P51 (P55899) · a predicted model of the same protein · chain C against A, TM-score 0.99
  • P61769 · AlphaFold monomer V2.0 prediction for beta-2-microglobulin (P61769) · a predicted model of the same protein · chain D against A, TM-score 0.99

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